CLINICAL STUDIES
Backed by science
Easy Meno
Red Clover
Evaluation of Clinical Meaningfulness of Red Clover (Trifolium pratense L.) Extract to Relieve Hot Flushes and Menopausal Symptoms in Peri- and Post-Menopausal Women: A Systematic Review and Meta- Analysis of Randomized Controlled Trials, Wiesław Kanadys 1, Agnieszka Barańska 1, Agata Błaszczuk 2, Małgorzata Polz-Dacewicz 2, Bartłomiej Drop 1, Krzysztof Kanecki 3, Maria Malm 1 -2021
The effect of red clover isoflavone supplementation over vasomotor and menopausal symptoms in postmenopausal women Markus Lipovac 1, Peter Chedraui, Christine Gruenhut, Anca Gocan, Christine Kurz, Benedikt Neuber, Martin Imhof , 2012
The Effect of Red Clover on Severity of Physical Menopause Symptoms Simin Tavoni1 , Fatemeh Shakeri , Hamid Haghani Seyyed Aahrafoddin Gooshehgir staavoni@iums.ac.ir ,2013
Black Cohosh
Black cohosh extracts in women with menopausal symptoms: an updated pairwise meta-analysis Ryoichi Sadahiro 1, Lillian Nohara Matsuoka 2, Bing-Syuan Zeng, Keng-Hsu Chen 3, Bing-Yan Zeng 4, Hung-Yu Wang 5, Che-Sheng Chu, Brendon Stubbs, Kuan-Pin Su, Yu-Kang Tu, Yi-Cheng Wu 6, Pao-Yen Lin, Tien-Yu Chen, Yen-Wen Chen 7, Mein-Woei Suen, Malcolm Hopwood, Wei-Cheng Yang, Cheuk-Kwan Sun, Yu- Shian Cheng, Yow-Ling Shiue 8, Chao-Ming Hung, Yutaka J Matsuoka 9, Ping-Tao Tseng, 2023
Efficacy of black cohosh (Cimicifuga racemosa L.) in treating early symptoms of menopause: a randomized clinical trial, 2013 Sakineh Mohammad-Alizadeh-Charandabi 1, Mahnaz Shahnazi 1, Jila Nahaee 1,✉, Somaei Bayatipayan
Exploring the Efficacy and Safety of Black Cohosh (Cimicifuga racemosa) in Menopausal Symptom Management, 2024 Kritiksha Hedaoo 1, Ankit K Badge 1, Yugeshwari R Tiwade 2, Nandkishor J Bankar 3, Vaishnavi H Mishra 3
Hypericum
The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial, 2019 Alieh Eatemadnia 1, Somayeh Ansari 2, Parvin Abedi 3, Shahnaz Najar 1
Vitex
Effect of Vitex agnus-castus on Menopausal Early Symptoms in Postmenopausal Women: A Randomized, Double Blind, Placebo –Controlled Study , 2011, Zahra Abbaspoor * Naiiere Azam Hajikhani Pourandokht Afshari
Lively Libido
Maca
A systematic review of the versatile effects of the Peruvian Maca Root (Lepidium meyenii ) on sexual dysfunction, menopausal symptoms and related conditions 2022, Cherie BowerCargill, Niousha Yarandi, Andrea Petróczi
Beneficial effects of Lepidium meyenii (Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women are not related to estrogen or androgen content , 2008 Nicole A Brooks 1 , Gisela Wilcox, Karen Z Walker, John F Ashton, Marc B C ox, Lily Stojanovska
Peruvian maca and possible impact on fertility, 2017 José́Manuel Lozano Sánchez,1 Zoraida Axtle Serrano,1 Julio Avilés Durán,2 Héctor Salvador Godoy Morales,2 Paola Berenice Merchand Álvarez,2 Ricardo Mera Mejía,2 Luis Felipe Montaño Estrada,3 Erika Patricia Rendón Huerta
A Meta-Analysis: Anti-Inflammatory Medicinal Plants for Age-Related Menopause-Like Symptoms and Psychological Problems in Breast Cancer and Healthy Perimenopausal Women , 2025 Fan Zhang 1, Dianhui Yang 2
Cordyceps
Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Medicinal Fungus Cordyceps with Its Nutraceutical and Therapeutic Potential Syed Amir Ashraf 1, Abd Elmoneim O Elkhalifa 1, Arif Jamal Siddiqui 2, Mitesh Patel 3, Amir Mahgoub Awadelkareem 1, Mejdi Snoussi 2,4, Mohammad Saquib Ashraf 5, Mohd Adnan 2,, Sibte Hadi 6,
Cordyceps spp.: A Review on Its Immune-Stimulatory and Other Biological Potentials Gitishree Das 1, Han-Seung Shin 2, Gerardo Leyva-Gómez 3, María L Del Prado-Audelo 3, Hernán Cortes 4, Yengkhom Disco Singh 5, Manasa Kumar Panda 6, Abhay Prakash Mishra 7, Manisha Nigam 8, Sarla Saklani 9, Praveen Kumar Chaturi 8, Miquel Martorell 10, Natália Cruz-Martins 11 12 13, Vineet Sharma 14, Neha Garg 15, Rohit Sharma 14, Jayanta Kumar Patra
Analysis of Metabolic Profiles and Antioxidant Activity of Chinese Cordyceps, Ophiocordyceps sinensis, and Paecilomyces hepiali Based on Untargeted Metabolomics Min He 1, Chu-Yu Tang 1, Tao Wang 1, Meng-Jun Xiao 1, Yu-Ling Li 1, Xiu-Zhang Li
Giant Angelica, Sok-Dan, Wilford's Cynanchum
The effect of herbal extract (EstroG-100) on pre-, peri- and post-menopausal women: a randomized double-blind, placebo-controlled study , 2012 Albert Chang 1, Bo-Yeon Kwak, Kwontaek Yi, Jae Soo Kim
Effects of Standardized Herbal Extract of Cynanchum wilfordii, Phlomis umbrosa, and Angelica gigas (EstroG-100®) on Physical Fatigue and Oxidative Stress in Vivo and in Vitro Yoon-Young Han 1, Joo-Hyun Oh 1, Ji-Min Kim 1, Bo-Mi Kim 1, Chan-Sung Park 1, Yong-Wook Lee 1, Minhee Lee 2, Jeongmin Lee 3
Evaluation of Efficacy and Safety of EstroG-100® in Alleviating Menopausal Symptoms in Postmenopausal Women in India: A Prospective, Single-center, Single-arm, Interventional Study , 2023 Hepzibah Kirubamani 1, Prachi Ahire 2, C Stalin 2
Estro G-100 herbal extract and hot flashes in postmenopausal women: A randomized double-blinded controlled trial Farah Farzaneh 1, Golnaz Fallah 2, Ahmad Khalili-Chelik 3, Adeleh Fallah 4, Maryamsadat Hosseini 1
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